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MINNEAPOLIS: George Springer reached base in all six plate appearances and hit two of Houston’s season-high six home runs to lead the Astros to their seventh straight victory, 17-6 over the Minnesota Twins on Wednesday.
Carlos Correa, Alex Bregman, Evan Gattis and Marwin Gonzalez also went deep for the Astros, who scored 40 runs in the three games to set a franchise record for runs in a series of any length. They had 19 hits on Wednesday and 37 in the series.
Brian Dozier, Eddie Rosario and Jason Castro homered for the Twins, who have lost four straight. Hector Santiago (4-5) gave up six runs and eight hits and walked three in six innings, three days after he was an emergency fill-in during the 15th inning of a loss to Tampa Bay.
Springer’s two homers traveled an estimated 900 combined feet, including a moon shot off of Ryan Pressly in the six-run seventh inning that landed just short of the third deck in left-center field. That was measured at 473 feet, the second-longest homer in the majors this season behind a 481-footer by Arizona’s Jake Lamb on April 29.
Michael Feliz (2-0) got the win and left-hander Reymin Guduan also made his big league debut, allowing one run on two hits in two innings.
Padres 2 Cubs 1: In San Diego, rookie Franchy Cordero tripled in the eighth and scored on Yangervis Solarte’s fielder’s choice as San Diego handed Chicago its season-high sixth straight loss.
Luis Perdomo and two relievers combined to hold the struggling Cubs to three hits. The rebuilding Padres won their season-high fourth straight game and swept the Cubs for the first time since Aug. 6-8, 2012.
The defending World Series champion Cubs, who were swept at the Dodgers during the weekend, finished their first winless trip of at least six games since Aug. 3-8, 2012, when they also lost three at Los Angeles and three at San Diego.
Overall the Cubs have lost seven in a row on the road.
Cordero, who made his big league debut on Saturday, tripled to right-center off Koji Uehara (1-3) leading off the eighth. Solarte hit a grounder to second baseman Ian Happ, whose throw home was not in time to get Cordero.
Brad Hand (1-3) pitched a perfect eighth for the win and Brandon Maurer pitched the ninth for his eighth save.
Orioles 10 Yankees 4: In Baltimore, Adam Jones homered and drove in five runs and Chris Davis added a two-run shot as Baltimore beat Masahiro Tanaka and New York.
Baltimore took two of three from the AL East leaders after coming in with a seven-game losing streak. The Yankees have lost 11 straight series in Baltimore — the second-longest road skid in franchise history behind a 12-series drought at Oakland from 1985-91.
Back in the lineup after missing four straight games with a sore hip, Jones contributed an RBI double to a four-run third inning, hit a three-run homer in the fourth and drove in a run with an infield hit in the eighth.
Tanaka (5-5) lost his fourth straight start, extending the longest streak of his career. The right-hander gave up seven runs and nine hits in 5 2/3 innings.
The Yankees had 11 hits but stranded 11 and went 1 for 12 with runners in scoring position.

Cardinals 2 Dodgers 1: In St. Louis, Dexter Fowler hit a tiebreaking homer in the eighth inning to back Carlos Martinez and give St. Louis a victory over Los Angeles.
Martinez (4-4) allowed one run and four hits while striking out nine as he pitched eight innings to help St. Louis snap a three-game losing streak.
Ross Stripling (0-3) lost for the first time since April 26 as he allowed Fowler’s seventh home run of the season, a 429-foot shot to right-center field. The Dodgers had their six-game winning streak end.
Seung-Hwan Oh pitched a scoreless ninth for his 12th save in 14 chances.
DDiamondbacks 6 Pirates 5, 14 innings: In Pittsburgh, Chris Owings singled home the go-ahead run in the 14th inning and Arizona outlasted Pittsburgh in a game that took more than 4½ hours to play — plus a 93-minute rain delay.
Paul Goldschmidt and Nick Ahmed homered for the Diamondbacks, who led in the ninth and 11th before finally putting away the Pirates. T.J. McFarland (3-0) pitched three hitless innings for the win.
Ahmed hit a solo shot in the 11th but Jordy Mercer tied the score in the bottom half with a home run of his own as steady showers began to fall. The game was delayed by rain after the 11th inning for 1 hour, 33 minutes.
David Peralta singled off Jhan Marinez (0-3) to start the 14th and advanced to second on Goldschmidt’s groundout. Jake Lamb was intentionally walked, and
Blue Jays 5 Reds 4: In Toronto, Devon Travis hit a tiebreaking two-run home run in the seventh inning and Luke Maile also hit a two-run home run as Toronto beat Cincinnati to complete a three-game sweep.
Jason Grilli (2-4) pitched one inning for the victory as the Blue Jays won for the eighth time in nine games and finished May at 18-10. Toronto hit 49 home runs in May, going deep in 18 of its final 20 games.
Joe Smith worked the eighth and Roberto Osuna survived a shaky ninth for his 11th save. Scott Schebler homered on Osuna’s first pitch, his NL-leading 16th. A single, Ryan Goins’ fielding error, and a stolen base gave the Reds runners at second and third with one out, but Osuna preserved the win by striking out Billy Hamilton and Zack Cozart.
Brewers 2 Mets 1: In New York, Eric Thames hit his first home run in three weeks, Keon Broxton also went deep against an ineffective Jacob deGrom, and Milwaukee beat New York for just its third win in 10 games.
Released by the Mets following a 50-game minor league drug suspension in 2009, Junior Guerra (1-0) defeated New York for the first time. He allowed four hits in six scoreless innings, struck out four and walked three, baffling batters with his splitter.
Athletics 3 Indians 1: In Cleveland, Sean Manaea allowed three hits in seven innings, Chad Pinder homered twice and drove in all three Oakland runs in a 3-1 win over Cleveland.
Manaea (4-3) retired the first 10 hitters before Francisco Lindor homered with one out in the fourth. He gave up singles to Daniel Robertson and Edwin Encarnacion, along with a walk to Jose Ramirez.
Pinder, the Athletics’ No. 9 hitter, hit a solo homer in the third and broke a 1-all tie with a two-run shot in the fifth.
Mike Clevinger (2-2) gave up both home runs.